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p15 INK4b Polyclonal antibody

p15 INK4b Polyclonal Antibody for IP, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IP, ELISA

Conjugate

Unconjugated

Cat no : 12877-1-AP

Synonyms

MTS2, CDKN2B, p14 INK4b, MTS-2, MTS 2



Tested Applications

Positive IP detected inHeLa cells

Recommended dilution

ApplicationDilution
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

WBSee 6 publications below

Product Information

12877-1-AP targets p15 INK4b in WB, IP, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen p15 INK4b fusion protein Ag3557
Full Name cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Calculated Molecular Weight 138 aa, 15 kDa
GenBank Accession NumberBC014469
Gene Symbol p15 INK4b/CDKN2B
Gene ID (NCBI) 1030
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Protocols

Product Specific Protocols
IP protocol for p15 INK4b antibody 12877-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Oncogene

CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A.

Authors - Q Tu
humanWB

EMBO Rep

MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.

Authors - Gongwei Wu
humanWB

Cell Cycle

Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs.

Authors - Jinliang Wu
mouseWB

Pancreatology

Smad4 deficiency substitutes Cdkn2b but not Cdkn2a downregulation in pancreatic cancer following induction of genetic events in adult mice.

Authors - Xintong Jia
humanWB

PLoS One

NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism.

Authors - Margita Márton
WB

Dis Model Mech

A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal.

Authors - Qiu Tu