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p15 INK4b Polyclonal antibody

p15 INK4b Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB,ELISA

Conjugate

Unconjugated

Cat no : 12877-1-AP

Synonyms

CDK4I, CDKN2B, INK4B, MTS 2, MTS2, Multiple tumor suppressor 2, p14 INK4b, P15, p15 INK4b, p15INK4b, TP15



Tested Applications

Recommended dilution

ApplicationDilution
Sample-dependent, check data in validation data gallery

Published Applications

WBSee 6 publications below

Product Information

12877-1-AP targets p15 INK4b in WB,ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen p15 INK4b fusion protein Ag3557
Full Name cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
Calculated molecular weight 138 aa, 15 kDa
GenBank accession numberBC014469
Gene symbol CDKN2B
Gene ID (NCBI) 1030
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Publications

SpeciesApplicationTitle
WB

Dis Model Mech

A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal.

Authors - Qiu Tu
humanWB

PLoS One

NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism.

Authors - Margita Márton
mouseWB

Pancreatology

Smad4 deficiency substitutes Cdkn2b but not Cdkn2a downregulation in pancreatic cancer following induction of genetic events in adult mice.

Authors - Xintong Jia
humanWB

Cell Cycle

Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs.

Authors - Jinliang Wu
humanWB

EMBO Rep

MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.

Authors - Gongwei Wu
mouseWB

Oncogene

CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A.

Authors - Q Tu