- Featured Product
- KD/KO Validated
p15 INK4b Polyclonal antibody
p15 INK4b Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
human and More (1)
Cat no : 12877-1-AP
|Sample-dependent, check data in validation data gallery|
12877-1-AP targets p15 INK4b in WB,ELISA applications and shows reactivity with human samples.
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||p15 INK4b fusion protein Ag3557|
|Full Name||cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)|
|Calculated molecular weight||138 aa, 15 kDa|
|GenBank accession number||BC014469|
|Gene ID (NCBI)||1030|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A.
MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation.
Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs.
Smad4 deficiency substitutes Cdkn2b but not Cdkn2a downregulation in pancreatic cancer following induction of genetic events in adult mice.
NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism.
Dis Model Mech
A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal.