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CLEC4G Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 18173-1-AP

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Tested Applications
Applications:
ELISA, WB, IHC
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18173-1-AP;HUVEC cells

HUVEC cells were subjected to SDS PAGE followed by western blot with 18173-1-AP( CLEC4G Antibody) at dilution of 1:300 incubated at 4 degree celsius over night

18173-1-AP;Transfected HEK-293 cells

Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 18173-1-AP (CLEC4G Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours

18173-1-AP;human tonsillitis tissue

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 18173-1-AP( CLEC4G Antibody) at dilution of 1:200 (under 10x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

18173-1-AP;human tonsillitis tissue

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 18173-1-AP( CLEC4G Antibody) at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Species specificity:
human
Positive WB detected in:
HUVEC cells, Transfected HEK-293 cells
Positive IHC detected in:
human tonsillitis tissue
Recommended dilution:
WB : 1:200-1:1000
IHC : 1:50-1:500

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
CLEC4G fusion protein ag12837
Full name:
C-type lectin domain family 4, member G
Calculated molecular weight:
293aa,33 kDa
Observed molecular weight:
40 kDa
GenBank accession number:
BC093691
Gene ID (NCBI):
339390
Gene symbol
CLEC4G
Synonyms
CLEC4G, LP2698, LSECtin, UNQ431
Background

CLEC4G, also known as LSECtin, is a member of the C-type lectin family of glycan-binding receptors that is expressed on sinusoidal endothelial cells in liver and lymph nodes. CLEC4G is a type II transmembrane protein of ∼40 kDa in size with a single C-type lectin-like domain at the COOH terminus, closest in homology to DC-SIGNR, DC-SIGN, and CD23. CLEC4G has been reported as a receptor for Japanese encephalitis virus (PubMed:24623090), ebolavirus (PubMed:16051304), SARS coronavirus/SARS-CoV (PubMed:16051304), lassa virus and Lymphocytic choriomeningitis virus glycoprotein (PubMed:22156524, PubMed:22673088).


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