Cannabinoid receptor 1 Recombinant antibody, PBS Only (Detector)

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  WB analysis of fetal human brain using 82787-3-RR (same clone as 82787-3-PBS)

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 82787-3-RR (CNR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82787-3-PBS in a different storage buffer formulation.

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  WB analysis using 82787-3-RR (same clone as 82787-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82787-3-RR (CNR1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82787-3-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP02192-2

  Cytometric bead array standard curve of MP02192-2, Cannabinoid receptor 1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 82787-5-PBS. Detection antibody: 82787-3-PBS. Standard: Ag12625. Range: 1.25-20 ng/mL.

Cannabinoid receptor 1 Uni-rAb^TM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Cat No. 82787-3-PBS

Clone No.250285B1

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Cytometric bead array, Indirect ELISA

Synonyms

CNR1, CANN6, cannabinoid receptor 1 (brain), CB R, CB1

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Product Information

82787-3-PBS targets Cannabinoid receptor 1 as part of a matched antibody pair:

MP02192-2: 82787-5-PBS capture and 82787-3-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Cannabinoid receptor 1 fusion protein Ag12625
• Full Name: cannabinoid receptor 1 (brain)
• Calculated Molecular Weight: 472 aa, 53 kDa
• Observed Molecular Weight: 60 kDa
• GenBank Accession Number: BC074812
• Gene Symbol: Cannabinoid receptor 1
• Gene ID (NCBI): 1268
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: P21554
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Cannabinoid receptor 1 (CNR1, or CB1) and CNR2 (CB2) are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family. The CB1 receptor is expressed mainly in the brain. The CB2 receptor is expressed mainly in the immune system and in hematopoietic cells. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana.