CXorf21 Recombinant monoclonal antibody, PBS Only

• Home
• Products
• Primary Antibodies
• Recombinant Antibodies
• CXorf21 Recombinant monoclonal antibody, PBS Only (88004-1-PBS)

• 

  WB analysis using 88004-1-RR (same clone as 88004-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 88004-1-RR (CXorf21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88004-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 88004-1-RR (same clone as 88004-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 88004-1-RR (CXorf21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88004-1-PBS in a different storage buffer formulation.

• 

  WB analysis of THP-1 using 88004-1-RR (same clone as 88004-1-PBS)

  THP-1 cells were subjected to SDS PAGE followed by western blot with 88004-1-RR (CXorf21 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 88004-1-PBS in a different storage buffer formulation.

• 

  IF Staining of THP-1 using 88004-1-RR (same clone as 88004-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using CXorf21 antibody (88004-1-RR, Clone: 260203H7 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 88004-1-PBS in a different storage buffer formulation.

CXorf21 Uni-rAb^® Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Cat No. 88004-1-PBS

Clone No.260203H7

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IF/ICC, Indirect ELISA

Synonyms

TASL, TLR adapter interacting with SLC15A4 on the lysosome

---

Product Information

88004-1-PBS targets CXorf21 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Ag32773

  Product name: Recombinant human CXorf21 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-301 aa of BC020611

  Sequence: MLSEGYLSGLEYWNDIHWSCASYNEQVAGEKEEETNSVATLSYSSVDETQVRSLYVSCKSSGKFISSVHSRESQHSRSQRVTVLQTNPNPVFESPNLAAVEICRDASRETYLVPSSCKSICKNYNDLQIAGGQVMAINSVTTDFPSESSFEYGPLLKSSEIPLPMEDSISTQPSDFPQKPIQRYSSYWRITSIKEKSSLQMQNPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASELIMTSVDQISLQVSREKNLETSKARDIVFSRLLQLMSTEITEISTPSLHISQYSNVNP

• Full Name: chromosome X open reading frame 21
• Observed Molecular Weight: 34 kDa
• GenBank Accession Number: BC020611
• Gene Symbol: CXorf21
• Gene ID (NCBI): 80231
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9HAI6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CXorf21 (Chromosome X open reading frame 21) is also named as TASL and TLR adapter interacting with SLC15A4 on the lysosome. CXorf21 is an innate immune adapter that mediates the recruitment and activation of IRF5 downstream of endolysosomal toll-like receptors TLR7, TLR8 and TLR9 (PMID:32433612). CXorf21 plays a role in the regulation of endolysosomal pH in immune cells such as B-cells, dendritic cells and monocytes (PMID: 31001245). CXorf21 is a mediator of the X-chromosome gene dose-dependent increased risk of SLE in females (PMID: 31695690).