Cystatin C Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66355-1-Ig |CloneNo.: 2E6F3

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Freight/Packing

Con: 225 μg/150 μl

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Species specificity:
human

Positive WB detected in:
fetal human brain tissue, human milk tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:3000
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cystatin C

Calculated molecular weight:
146aa,16 kDa

Observed molecular weight:
13 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CST3

Synonyms
ARMD11, CST3, Cystatin 3, Cystatin C, Gamma trace, Post gamma globulin
Background

Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration, shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus.


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