ETV6 Polyclonal antibody, PBS Only

• 

  WB analysis using 13182-1-AP (same clone as 13182-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13182-1-AP (ETV6 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13182-1-PBS in a different storage buffer formulation.

ETV6 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 13182-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

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Product Information

13182-1-PBS targets ETV6 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag3852

  Product name: Recombinant human ETV6 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-355 aa of BC043399

  Sequence: MSETPAQCSIKQERISYTPPESPVPSYASSTPLHVPVPRALRMEEDSIRLPAHLRLQPIYWSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHILKQRKPRILFSPFFHPGNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLHRSRSPITTNHRPSPDPEQRPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPMENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPRHSVDFKQSRLSEDGLHREGKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYE

• Full Name: ets variant 6
• Calculated Molecular Weight: 452 aa, 53 kDa
• Observed Molecular Weight: 57-65 kDa
• GenBank Accession Number: BC043399
• Gene Symbol: ETV6
• Gene ID (NCBI): 2120
• RRID: AB_2246688
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P41212
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

ETV6, the E26 transformation-specific (ETS) family transcription repressor and tumor suppressor variant 6 gene, resides on chromosome 12p13, encodes a 57 kDa ETS family transcription factor with 3 highly conserved functional domains(PMID: 32841218). ETV6 is a well-studied hematopoietic transcription factor reported to play a key functional role in hematopoiesis, megakaryopoiesis, cell growth, and differentiation.