Fc Epsilon RI Alpha Polyclonal antibody

Fc Epsilon RI Alpha Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 10980-1-AP


Fc epsilon RI alpha, FCE1A, FCER1A, FcERI, FceRIa, IgE Fc receptor subunit alpha

Tested Applications

Positive WB detected inMC/9 cells, human spleen tissue, RAW 264.7 cells, mouse spleen tissue, rat spleen tissue

Recommended dilution

Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10980-1-AP targets Fc Epsilon RI Alpha in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Fc Epsilon RI Alpha fusion protein Ag1398
Full Name Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Calculated Molecular Weight 30 kDa
Observed Molecular Weight 55-70 kDa
GenBank Accession NumberBC015195
Gene Symbol FCER1A
Gene ID (NCBI) 2205
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Fc fragment of IgE, high affinity I, receptor for, alpha polypeptide, also known as high affinity immunoglobulin epsilon receptor subunit alpha, FCER1A and FCE1A, is a single-pass type I membrane protein which contains 2 immunoglobulin-like domains. FCER1A is a subunit of the IgE receptor, which is composed of one glycosylated alpha (FCER1A), one beta (FCER1B), and two gamma (FCER1G) subunits. The high affinity IgE receptor plays a central role in allergic disease, coupling allergen and mast cells to initiate the inflammatory and immediate hypersensitivity responses that are characteristic of disorders such as hay fever and asthma. The calculated molecular weight of FCER1A is 30 kDa, the 55- to 70-kDa bands detected by this antibody are probably caused by heterogeneous glycosylation (PMID: 11344350; 12671054).


Product Specific Protocols
WB protocol for Fc Epsilon RI Alpha antibody 10980-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




Response to Comment on "Tumor-initiating cells establish an IL-33-TGF-β niche signaling loop to promote cancer progression".

Authors - Sachiko Taniguchi

J Allergy Clin Immunol

Mast cell-associated alveolar inflammation in patients with atopic uncontrolled asthma.

Authors - Andersson Cecilia K CK

J Allergy Clin Immunol

Thymic stromal lymphopoietin epigenetically upregulates Fc receptor γ subunit-related receptors on antigen-presenting cells and induces TH2/TH17 polarization through dectin-2.

Authors - Yunsheng Liang

Transl Res

Allergic asthma aggravates angiotensin Ⅱ-induced cardiac remodeling in mice.

Authors - Chi Geng
  • KO Validated


Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p.

Authors - Hongmei Zhao


Novel site-specific mast cell subpopulations in the human lung.

Authors - Andersson C K CK