FOXC1 Monoclonal antibody

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• FOXC1 Monoclonal antibody (66568-1-Ig)

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FOXC1 Monoclonal Antibody for WB, ELISA

Cat No. 66568-1-Ig Copied!

Clone No. 1F4E11

Publications (1)

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Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, ELISA

Synonyms

FREAC 3, Forkhead-related transcription factor 3, Forkhead-related protein FKHL7, FKHL7, ARA

• 

  WB analysis using 66568-1-Ig

  Various cells were subjected to SDS PAGE followed by western blot with 66568-1-Ig (FOXC1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
• 

  WB analysis of HEK-293 using 66568-1-Ig

  WB result of FOXC1 antibody (66568-1-Ig; 1:10000; incubated at room temperature for 1.5 hours) with sh-Control and sh-FOXC1 transfected HEK-293 cells.

  This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy

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Tested Applications

• Positive WB detected in: HeLa cells, HEK-293 cells, HEK293 cells, L02 cells, HepG2 cells

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:20000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

66568-1-Ig targets FOXC1 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Mouse / IgG1
• Class: Monoclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: forkhead box C1
• Calculated Molecular Weight: 57 kDa
• Observed Molecular Weight: 70-75 kDa
• GenBank Accession Number: NM_001453
• Gene Symbol: FOXC1
• Gene ID (NCBI): 2296
• RRID: AB_2881929
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein G purification
• UNIPROT ID: Q12948
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FOXC1, also named as FKHL7 and FREAC3, binding of FREAC-3 and FREAC-4 to their cognate sites results in bending of the DNA at an angle of 80-90 degrees. Defects in FOXC1 are the cause of Axenfeld-Rieger syndrome type 3 (RIEG3). Defects in FOXC1 are the cause of iridogoniodysgenesis anomaly (IGDA). Defects in FOXC1 are a cause of Peters anomaly.

Publications

What published studies show

The FOXC1 Monoclonal antibody (1F4E11), catalog number 66568-1-Ig, has a total of 1 citation. It appears in Journal of Advanced Research (IF 17.1), published in December 2025. The cited study, which used this antibody for Western Blot in human samples, focuses on diabetic wound healing, specifically exploring FBP1 as a novel therapeutic target and the role of asiatic acid-hydrogen sulfide donors in accelerating wound repair.

Automatically generated from the 1 publication citations by Able AI.

• Human
• Mouse
• Rat
• Monkey
• Pig

Species	Application	Title
human	WB	J Adv Res; Discovery of FBP1 as novel therapeutic target and asiatic acid-hydrogen sulfide donors accelerate diabetic wound healing.; Authors - Shenglin Wang