ALR Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 11293-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 54 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
A375 cells, A431 cells, mouse liver tissue, rat liver tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human colon cancer tissue, human liver tissue, human testis tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
growth factor, augmenter of liver regeneration

Calculated molecular weight:
15 kDa,23 kDa

Observed molecular weight:
23-25 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GFER

Synonyms
ALR, ERV1, GFER, Hepatopoietin, HERV1, HPO, HPO1, HPO2, HSS
Background

GFER (FAD-linked sulfhydryl oxidase) is also named as ALR, HERV1, HPO. It plays an important role in the disulfide relay system (DRS) in human mitochondria. The GFER gene codes for 2 distinct isoforms that are probably synthesized from the same mRNA with the use of different initiation codons. The long isoform (205 amino acids, 23/21 kD) is located mainly in the mitochondrial intermembrane space and exists under nonreducing and nondenaturing conditions as a homodimer and a heterodimer. The shorter isoform (125 amino acids, 15 kD), which lacks 80 amino acids at its N terminus compared to the longer isoform, is present predominantly in the nucleus (PMID: 19409522, 24880092, 21152698).


Back
to top