ALR Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 11293-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 54 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
A375 cells, A431 cells, mouse liver tissue, rat liver tissue

Positive IP detected in:
mouse liver tissue

Positive IHC detected in:
human colon cancer tissue, human liver tissue, human testis tissue

Recommended dilution:
WB : 1:500-1:1000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
growth factor, augmenter of liver regeneration

Calculated molecular weight:
15 kDa,23 kDa

Observed molecular weight:
23-25 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GFER

Synonyms
ALR, ERV1, GFER, Hepatopoietin, HERV1, HPO, HPO1, HPO2, HSS
Background

GFER(FAD-linked sulfhydryl oxidase) is also named as ALR, HERV1, HPO. It plays an important role in the disulfide relay system (DRS) in human mitochondria.The GFER gene codes for 2 distinct isoforms that are probably synthesized from the same mRNA with the use of different initiation codons. The long isoform (205 amino acids, 23 kD) is located mainly in the mitochondrial intermembrane space and exists under nonreducing and nondenaturing conditions as a homodimer and a heterodimer. The shorter isoform (125 amino acids, 15 kD), which lacks 80 amino acids at its N terminus compared to the longer isoform, is present predominantly in the nucleus(PMID:19409522).


Back
to top