GIPC3-Specific Polyclonal antibody, PBS Only

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  WB analysis using 25479-1-AP (same clone as 25479-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 25479-1-AP (GIPC3-Specific antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25479-1-PBS in a different storage buffer formulation.

GIPC3-Specific Polyclonal Antibody for WB, Indirect ELISA

Cat No. 25479-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

25479-1-PBS targets GIPC3-Specific in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: GIPC PDZ domain containing family, member 3
• Calculated Molecular Weight: 34 kDa
• Observed Molecular Weight: 40 kDa
• GenBank Accession Number: NM_133261
• Gene Symbol: GIPC3
• Gene ID (NCBI): 126326
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8TF64
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Human PDZ domain-containing protein GIPC3 is a member of the GIPC (GAIP-interacting protein C-terminus) gene family, which is characterized by a single, conserved PDZ domain and GIPC homology (GH1 and GH2) domains. Aberrant expression of GIPC3 has been evidenced to correlate to the audiogenic seizures and sensorineural hearing loss in mouse and human (PMID: 36301034, 21326233). GIPC3 is upregulated in multiple cancer types, with a significant positive correlation of its expression with Hh signaling identified in melanoma cell lines (PMID: 34224745). This antibody is highly specific for GIPC3 protein.