GRM1/mGluR1 Recombinant monoclonal antibody

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  WB analysis of mouse brain using 86280-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 86280-1-RR (GRM1/mGluR1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of rat brain using 86280-1-RR

  rat brain tissue were subjected to SDS PAGE followed by western blot with 86280-1-RR (GRM1/mGluR1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

GRM1/mGluR1 Uni-rAb^® Recombinant Antibody for WB, ELISA

Cat No. 86280-1-RR

Clone No.250635C9

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Synonyms

GRM1, MGLUR1, GPRC1A, GRM1A, mGlu1

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Tested Applications

• Positive WB detected in: rat brain tissue, mouse brain tissue

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

86280-1-RR targets GRM1/mGluR1 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: glutamate receptor, metabotropic 1
• Calculated Molecular Weight: 132 kDa
• Observed Molecular Weight: 130-140 kDa
• GenBank Accession Number: NM_000838
• Gene Symbol: GRM1
• Gene ID (NCBI): 2911
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q13255
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

GRM1, also named as GPRC1A and MGLUR1, belongs to the G-protein coupled receptor 3 family. GRM1 is a receptor for glutamate. The activity of GRM1 is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. It may participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.