Recombinant Human LILRA1 protein (His Tag)

Species

Human

Purity

>90 %, SDS-PAGE

Tag

His Tag

Activity

not tested

Cat no : Eg4704

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Validation Data Gallery

• 

  Purity of Recombinant Human LILRA1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

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Product Information

• Purity: >90 %, SDS-PAGE
• Endotoxin: <0.1 EU/μg protein, LAL method
• Activity:

  Not tested

• Expression: HEK293-derived Human LILRA1 protein Pro17-Asn461 (Accession# O75019-1) with a His tag at the C-terminus.
• GeneID: 11024
• Accession: O75019-1
• PredictedSize: 49.6 kDa
• SDS-PAGE: 60-75kDa, reducing (R) conditions
• Formulation: Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
• Reconstitution: Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
• Storage Conditions:
  It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
• Shipping: The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

Leukocyte immunoglobulin-like receptor A1 (LILRA1) plays a significant role in the immune system. It is part of the leukocyte immunoglobulin-like receptor (LIR) family. The LILRA1 is predominantly expressed in B cells, where it interacts with major histocompatibility complex class I ligands and contributes to the regulation of immune responses. LILRA1 is involved in various pathways, including the innate immune system and Class I MHC-mediated antigen processing and presentation. It is known to have multiple functions, such as acting as a receptor for class I MHC antigens and potentially playing a role in the recognition and modulation of immune responses.

References:

1. Tedla N. et al. (2011). Tissue Antigens. 77(4):305–316.
2. Hogan LE. et al.(2016). Sci Rep. 6(1):21780.
3. Hirayasu K. et al. (2015). J Hum Genet. 60(11):703–708.
4. An H. et al. (2010). J Rheumatol.37(8):1596–1606.