APC Anti-Mouse IL-4 (11B11)

IL-4 Monoclonal Antibody for FC (Intra)

Host / Isotype

Rat / IgG1, kappa




FC (Intra)


APC Fluorescent Dye



Cat no : APC-65074


Il 4, Il4, IL-4, interleukin 4

Tested Applications

Positive FC detected in PMA and ionomycin stimulated mouse Th2-polarized splenocytes

Recommended dilution

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

APC-65074 targets IL-4 in FC (Intra) applications and shows reactivity with Mouse samples.

Tested Reactivity Mouse
Host / Isotype Rat / IgG1, kappa
Class Monoclonal
Type Antibody
Immunogen Partially purified native mouse IL-4
Full Name interleukin 4
GenBank Accession NumberBC027514
Gene Symbol IL-4
Gene ID (NCBI) 16189
Conjugate APC Fluorescent Dye
Excitation/Emission Maxima Wavelengths650 nm / 660 nm
Form Liquid
Purification MethodAffinity purification
Storage Buffer Phosphate based buffer with 0.09% sodium azide and 0.1% gelatin, pH 7.2.
Storage ConditionsStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Background Information

Interleukin-4 (IL-4), a member of the α-helical cytokine family, is produced by activated CD4+ T cells, basophils, and mast cells. It promotes the proliferation and differentiation of antigen presenting cells. IL-4 also plays a pivotal role in antibody isotype switching and stimulates the production of IgE. This cytokine has been applied in the treatment of autoimmune disorder like multiple myeloma, cancer, psoriasis, and arthritis. IL-4 has also been extensively applied to inhibit detrimental effect of Th1. It may promote the growth of epithelial tumors by mediating increased proliferation and survival. (PMID: 24489573;3049907;21663408)


Product Specific Protocols
FC protocol for APC IL-4 antibody APC-65074Download protocol
Standard Protocols
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