IQGAP2 Polyclonal antibody

IQGAP2 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 30692-1-AP

Synonyms

IQGAP2

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Validation Data Gallery

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  WB analysis using 30692-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 30692-1-AP (IQGAP2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HepG2 cells, HuH-7 cells, Ramos cells, human peripheral blood platelets, mouse testis tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

30692-1-AP targets IQGAP2 in WB, ELISA applications and shows reactivity with Human, mouse samples.

• Tested Reactivity: Human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: IQGAP2 fusion protein Ag33518
• Full Name: IQ motif containing GTPase activating protein 2
• Calculated Molecular Weight: 181 kDa
• Observed Molecular Weight: 181 kDa
• GenBank Accession Number: NM_006633
• Gene Symbol: IQGAP2
• Gene ID (NCBI): 10788
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

IQGAP2, a member of the IQGAP family, functions as a tumor suppressor in most of the cancers. IQGAP2 contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. IQGAP2 interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. It also acts as a tumor suppressor and has been found to play a role in regulating innate antiviral responses.