Anti-Mouse Integrin beta 5 Rabbit Recombinant Antibody

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• Anti-Mouse Integrin beta 5 Rabbit Recombinant Antibody (98706-1-RR)

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  FC experiment of bEnd.3 using 98706-1-RR

  1x10^6 bEnd.3 cells were surface stained with 0.25 ug Anti-Mouse Integrin beta 5 Rabbit RecAb (98706-1-RR, Clone: 252748H5) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  Affinity of 98706-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98706-1-RR against Mouse Integrin beta 5 were performed. The affinity constant is 2.84 nM.

Integrin beta 5 Uni-rAb^® Recombinant Antibody for FC

Cat No. 98706-1-RR

Clone No.252748H5

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

Integrin beta-5, Itgb5

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Tested Applications

• Positive FC detected in: bEnd.3 cells

Recommended dilution

• Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension

This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

98706-1-RR targets Integrin beta 5 in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  CatNo: Eg10456

  Product name: Recombinant mouse ITB5 protein

  Source: mammalian cells-derived, pHZ-KIsec-C-6*HIS

  Tag: C-Twin-Strep-Tag

  Domain: 10011459 of

  Sequence: \

• Full Name: integrin beta 5
• Gene Symbol: Itgb5
• Gene ID (NCBI): 16419
• RRID: AB_3746287
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
• Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.

Background Information

Integrin beta-5 (ITGB5) is expected to be located in the plasma membrane and mitochondria, which is i ubiquitinated in placenta and gall bladder. ITGB5 is a member of integrins and was proved to be associated with pathological processes in several tumors (PMID: 34966851). It is reported that TGB5 is highly expressed in hepatocellular carcinoma (HCC), and miR-185 regulates the expression of β- catenin through the ITGB5-dependent manner and affects the proliferation and migration of HCC cells (PMID: 35223869).