Product Information
14236-1-PBS targets LIV-1/ZIP6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Reactivity | human, mouse, rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | LIV-1/ZIP6 fusion protein Ag5478 Predict reactive species |
Full Name | solute carrier family 39 (zinc transporter), member 6 |
Calculated Molecular Weight | 85 kDa |
Observed Molecular Weight | 85-100 kDa, 48 and 32 kDa |
GenBank Accession Number | BC039498 |
Gene Symbol | SLC39A6/ZIP6 |
Gene ID (NCBI) | 25800 |
RRID | AB_10596924 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q13433 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
The zinc transporter LIV-1 (also known as SLC39A6 or ZIP6) was originally identified as an estrogen-induced gene in breast cancer cells. Elevated LIV-1 expression is reportedly related to cancer progression in various types of cancer, including breast, prostate, pancreatic, cervical and liver cancers. While correlation of LIV-1 and prognosis may vary. LIV 1 has 3 isoforms with MW of 85-100 (glycosylation and phosphorylation), 48 and 32 kDa while migrates as different bands in different lysates in SDS-PAGE.