LYNX1 Polyclonal antibody

LYNX1 Polyclonal Antibody for IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC,ELISA

Conjugate

Unconjugated

Cat no : 13373-1-AP

Synonyms

Ly6/neurotoxin 1, LYNX1, SLURP 2, SLURP2

---

Validation Data Gallery

• 

  IHC staining of human oesophagus cancer using 13373-1-AP

  Immunohistochemical analysis of paraffin-embedded human oesophagus cancer tissue slide using 13373-1-AP (LYNX1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human oesophagus cancer using 13373-1-AP

  Immunohistochemical analysis of paraffin-embedded human oesophagus cancer tissue slide using 13373-1-AP (LYNX1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human oesophagus using 13373-1-AP

  Immunohistochemical analysis of paraffin-embedded human oesophagus tissue slide using 13373-1-AP (LYNX1 Antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of human oesophagus using 13373-1-AP

  Immunohistochemical analysis of paraffin-embedded human oesophagus tissue slide using 13373-1-AP (LYNX1 Antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of human oesophagus cancer using 13373-1-AP

  Immunohistochemical analysis of paraffin-embedded human oesophagus cancer tissue slide using 13373-1-AP (LYNX1 Antibody) at dilution of 1:50 (under 40x lens).

• 

  IHC staining of mouse brain using 13373-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 13373-1-AP (LYNX1 Antibody) at dilution of 1:50 (under 10x lens).

• 

  IHC staining of mouse brain using 13373-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 13373-1-AP (LYNX1 Antibody) at dilution of 1:50 (under 40x lens).

---

Tested Applications

• Positive IHC detected in: human oesophagus cancer tissue, mouse brain tissue, human oesophagus tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

13373-1-AP targets LYNX1 in IHC,ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: LYNX1 fusion protein Ag4195
• Full Name: Ly6/neurotoxin 1
• Calculated Molecular Weight: 131 aa, 14 kDa
• GenBank Accession Number: BC032306
• Gene Symbol: LYNX1
• Gene ID (NCBI): 66004
• RRID: AB_2877944
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

LYNX1, also named as SLURP2, is a neuronal membrane molecule related to snake a-neurotoxins able to modulate nicotinic acetylcholine receptors (nAChRs). It acts in different tissues through interaction to nAChRs to balance neuronal activity.