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Tested Applications
| Positive WB detected in | COLO 320 cells, mouse small intestine tissue |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:500-1:2000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
32828-1-AP targets MEP1B in WB, ELISA applications and shows reactivity with human, mouse samples.
| Tested Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
Recombinant protein Predict reactive species |
| Full Name | meprin A, beta |
| Calculated Molecular Weight | 80 kDa |
| Observed Molecular Weight | 100 kDa |
| GenBank Accession Number | NM_001308171.1 |
| Gene Symbol | MEP1B |
| Gene ID (NCBI) | 4225 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity Purification |
| UNIPROT ID | Q16820 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
MEP1B, also known as meprin A subunit beta, is a gene that encodes a metalloprotease belonging to the Astacins family of zinc endopeptidases. The MEP1B gene is highly expressed in the small intestine and duodenum, and it is also expressed in the kidneys, leukocytes, and certain cancer cells. MEP1B encodes a metalloprotease that plays a key role in the hydrolysis of various substrates, including collagen, laminin, and elastin, which are major components of the extracellular matrix. This function is crucial for tissue development, repair, and remodeling.
Protocols
| Product Specific Protocols | |
|---|---|
| WB protocol for MEP1B antibody 32828-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
