Mammaglobin B Polyclonal antibody

Mammaglobin B Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 21211-1-AP

Synonyms

Lacryglobin, LIPHC, Lipophilin C, LPHC, Mammaglobin 2, Mammaglobin B, MGB2, SCGB2A1, UGB3

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Validation Data Gallery

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  IHC staining of human ovary tumor using 21211-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 21211-1-AP (Mammaglobin B antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human ovary tumor using 21211-1-AP

  Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 21211-1-AP (Mammaglobin B antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human breast cancer using 21211-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 21211-1-AP (Mammaglobin B antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human breast cancer using 21211-1-AP

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 21211-1-AP (Mammaglobin B antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Tested Applications

• Positive IHC detected in: human ovary tumor tissue, human breast cancer tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

21211-1-AP targets Mammaglobin B in IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Mammaglobin B fusion protein Ag15609
• Full Name: secretoglobin, family 2A, member 1
• Calculated Molecular Weight: 95 aa, 11 kDa
• GenBank Accession Number: BC062218
• Gene Symbol: SCGB2A1
• Gene ID (NCBI): 4246
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Mammaglobin B, also referred to as secretoglobin family 2A member 1 (SCGB2A1), is a member of the uteroglobin superfamily. SCGB2A1 has been identified as a candidate biomarker for the detection of lymph node micrometastases in breast cancer and abdominal cancer types. SCGB2A1 has been considered as a promising diagnostic marker for occult tumor cells in effusions of several malignancies and as a potential immunotherapeutic target in ovarian cancer.