iNOS Antibody 20 Publications

Rabbit Polyclonal| Catalog number: 18985-1-AP

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Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat, chicken

Positive WB detected in:
HeLa cells

Positive IHC detected in:
human liver tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:100-1:400
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
nitric oxide synthase 2, inducible

Calculated molecular weight:
131 kDa

Observed molecular weight:
130-140 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
NOS2

Synonyms
HEP NOS, Hepatocyte NOS, Inducible NO synthase, Inducible NOS, INOS, NOS, NOS type II, NOS2, NOS2A
Background

NOS2, also named as iNOS and NOS2A, produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. NO is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. NOS2 is a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. This antibody is specific to NOS2.


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