Orm1 Polyclonal antibody

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  WB analysis using 32498-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 32498-1-AP (Orm1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Orm1 Polyclonal Antibody for WB, ELISA

Cat No. 32498-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, ELISA

Synonyms

A1AG1, AGP 1, Alpha-1-acid glycoprotein 1, OMD 1, Orosomucoid-1

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Tested Applications

• Positive WB detected in: mouse kidney tissue, PNGF treated mouse kidney tissue

Recommended dilution

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

32498-1-AP targets Orm1 in WB, ELISA applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Orm1 fusion protein Eg2752
• Full Name: orosomucoid 1
• Calculated Molecular Weight: 24 kDa
• Observed Molecular Weight: 23-44 kDa
• GenBank Accession Number: NM_008768.2
• Gene Symbol: Orm1
• Gene ID (NCBI): 18405
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q60590
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Orosomucoid-1 (ORM1), also called Alpha-1-acid glycoprotein 1 (AGP1), is a glycoprotein synthesized mostly by hepatocytes. ORM1 is an acute-phase reactant protein controlled by glucocorticoids, interleukin-1 and interleukin-6, and increase up to 5-50 times upon infection and/or inflammation. Anti-apoptotic effect and role as immunomodulator of ORM have been reported. ORM is an important carrier for synthetic drugs and influences their distribution and availability in the body. This antibody recognizes a band about 44 kDa in mouse kidneys which is due to the glycosylation of ORM1.