Anti-Mouse P-Selectin/CD62P Rabbit Recombinant Antibody, PBS Only

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  FC experiment of mouse peripheral blood platelets using 98302-2-RR (same clone as 98302-2-PBS)

  1x10^6 Thrombin treated mouse peripheral blood platelets were surface stained with 0.25 ug Anti-Mouse P-Selectin/CD62P Rabbit RecAb (98302-2-RR, Clone: 240766F5) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Untreated mouse peripheral blood platelets were surface stained with 0.25 ug Anti-Mouse P-Selectin/CD62P Rabbit RecAb (98302-2-RR, Clone: 240766F5) and PE-conjugated Goat Anti-Rabbit IgG (black, dashed). Cells were not fixed. This data was developed using the same antibody clone with 98302-2-PBS in a different storage buffer formulation.

P-Selectin/CD62P Uni-rAb^® Recombinant Antibody for FC

Cat No. 98302-2-PBS

Clone No.240766F5

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Synonyms

P-selectin, CD62P, 240766F5, PADGEM, P selectin

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Product Information

98302-2-PBS targets P-Selectin/CD62P in FC applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: selectin, platelet
• Calculated Molecular Weight: 83 kDa
• GenBank Accession Number: NM_011347.2
• Gene Symbol: Selp
• Gene ID (NCBI): 20344
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q01102
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.