PAX2 Polyclonal antibody

PAX2 Polyclonal Antibody for ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (1)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Publications

9

Cat no : 21385-1-AP

Synonyms

paired box 2, Paired box protein Pax 2, PAX2

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Validation Data Gallery

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Recommended dilution

Application	Dilution
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Published Applications

• WB: See 1 publications below
• IHC: See 4 publications below
• IF: See 4 publications below

Product Information

The immunogen of 21385-1-AP is PAX2 Fusion Protein expressed in E. coli.

• Tested Reactivity: human
• Cited Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: PAX2 fusion protein Ag16020
• Full Name: paired box 2
• Calculated Molecular Weight: 431 aa, 46 kDa
• GenBank Accession Number: BC148710
• Gene Symbol: PAX2
• Gene ID (NCBI): 5076
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

PAX2 is a transcription factor, primarily expressed during embryonic development. It has a critical role in the development of the urogenital tract, the eyes, and the CNS. It plays a key role during renal development and to act as an oncogene favoring renal tumor growth. PAX2 was suggested as a sensitive and highly specific marker for renal cell carcinoma (RCC).

Publications

Species	Application	Title
mouse	IF	Dev Cell; A Synthetic Niche for Nephron Progenitor Cells.; Authors - Aaron C Brown
human	IHC	NPJ Genom Med; Integrated diagnosis based on transcriptome analysis in suspected pediatric sarcomas.; Authors - Daisuke Ichikawa
mouse	IF	Sci Rep; Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum.; Authors - Jun Ju
	IHC	Exp Neurol; Preterm birth disrupts cerebellar development by affecting granule cell proliferation program and Bergmann glia.; Authors - Igor Y Iskusnykh
mouse	IF	Sci Rep; β-catenin regulates the formation of multiple nephron segments in the mouse kidney.; Authors - Patrick Deacon
mouse	IHC	Neuroscience; Lmx1a and Lmx1b are Redundantly Required for the Development of Multiple Components of the Mammalian Auditory System.; Authors - Victor V Chizhikov