Published Applications
| WB | See 1 publications below |
| IHC | See 4 publications below |
| IF | See 4 publications below |
Product Information
21385-1-AP targets PAX2 in WB, IF, IHC, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Cited Reactivity | human, mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen |
CatNo: Ag16020 Product name: Recombinant human PAX2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 145-432 aa of BC148710 Sequence: QPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVGSYSINGILGIPRSNGEKRKRDEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRADTFTQQQLEALDRVFERPSYPDVFQASEHIKSEQGNEYSLPALTPGLDEVKSSLSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPPTGQGSYPTSTLAGMVPGSEFSGNPYSHPQYTAYNEAWRFSNPALLMPPPGPPLPLLPLPMTATSYRGDHIKLQADSFGLHIVPV Predict reactive species |
| Full Name | paired box 2 |
| Calculated Molecular Weight | 431 aa, 46 kDa |
| GenBank Accession Number | BC148710 |
| Gene Symbol | PAX2 |
| Gene ID (NCBI) | 5076 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | Q02962 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
PAX2 is a transcription factor, primarily expressed during embryonic development. It has a critical role in the development of the urogenital tract, the eyes, and the CNS. It plays a key role during renal development and to act as an oncogene favoring renal tumor growth. PAX2 was suggested as a sensitive and highly specific marker for renal cell carcinoma (RCC).
Publications
| Species | Application | Title |
|---|---|---|
NPJ Genom Med Integrated diagnosis based on transcriptome analysis in suspected pediatric sarcomas. | ||
Sci Rep Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum. | ||
Exp Neurol Preterm birth disrupts cerebellar development by affecting granule cell proliferation program and Bergmann glia. | ||
Sci Rep β-catenin regulates the formation of multiple nephron segments in the mouse kidney. | ||
Neuroscience Lmx1a and Lmx1b are Redundantly Required for the Development of Multiple Components of the Mammalian Auditory System. |
