PDRG1 Recombinant antibody

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  WB analysis using 85851-4-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 85851-4-RR (PDRG1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

PDRG1 Uni-rAb^TM Recombinant Antibody for WB, ELISA

Cat No. 85851-4-RR

Clone No.250203E9

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, ELISA

Synonyms

C20orf126, p53 and DNA damage regulated 1, p53 and DNA damage-regulated protein 1, PDRG

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Tested Applications

• Positive WB detected in: HEK-293 cells, HeLa cells, Jurkat cells, A549 cells, MCF-7 cells, rat liver tissue

Recommended dilution

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

85851-4-RR targets PDRG1 in WB, ELISA applications and shows reactivity with human, rat samples.

• Tested Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: PDRG1 fusion protein Ag9109
• Full Name: p53 and DNA damage regulated 1
• Calculated Molecular Weight: 16 kDa
• Observed Molecular Weight: 15-16 kDa
• GenBank Accession Number: BC009334
• Gene Symbol: PDRG1
• Gene ID (NCBI): 81572
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9NUG6
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

PDRG1 codes for a novel protein called p53 and DNA damage-regulated protein 1. Human PDRG1 is predominantly expressed in normal testis and its expression can be induced by UV irradiation and be repressed by p53 [PMID14562055]. Recently, PDRG1 was identified as a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress. Its expression was upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to normal tissues [PMID: 21193842], suggesting its being a novel tumor marker that could play a role in cancer development and/or progression.