PDRG1 Recombinant antibody, PBS Only

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  WB analysis using 85851-4-RR (same clone as 85851-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85851-4-RR (PDRG1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85851-4-PBS in a different storage buffer formulation.

PDRG1 Uni-rAb^TM Recombinant Antibody for WB, Indirect ELISA

Cat No. 85851-4-PBS

Clone No.250203E9

Host / Isotype

Rabbit / IgG

Reactivity

human, rat

Applications

WB, Indirect ELISA

Synonyms

C20orf126, p53 and DNA damage regulated 1, p53 and DNA damage-regulated protein 1, PDRG

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Product Information

85851-4-PBS targets PDRG1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.

• Tested Reactivity: human, rat
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: PDRG1 fusion protein Ag9109
• Full Name: p53 and DNA damage regulated 1
• Calculated Molecular Weight: 16 kDa
• Observed Molecular Weight: 15-16 kDa
• GenBank Accession Number: BC009334
• Gene Symbol: PDRG1
• Gene ID (NCBI): 81572
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9NUG6
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

PDRG1 codes for a novel protein called p53 and DNA damage-regulated protein 1. Human PDRG1 is predominantly expressed in normal testis and its expression can be induced by UV irradiation and be repressed by p53 [PMID14562055]. Recently, PDRG1 was identified as a novel tumor marker for multiple malignancies that is selectively regulated by genotoxic stress. Its expression was upregulated in multiple malignancies including cancers of the colon, rectum, ovary, lung, stomach, breast and uterus when compared to normal tissues [PMID: 21193842], suggesting its being a novel tumor marker that could play a role in cancer development and/or progression.