PDS5B Polyclonal antibody, PBS Only

PDS5B Polyclonal Antibody for WB, Indirect ELISA

Cat No. 28318-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Androgen-induced proliferation inhibitor, Androgen-induced prostate proliferative shutoff-associated protein AS3, APRIN, AS3, CG008

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

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Product Information

28318-1-PBS targets PDS5B in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PDS5B fusion protein Ag27977 Predict reactive species
Full Name PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
Calculated Molecular Weight 165 aa
Observed Molecular Weight150 kDa
GenBank Accession NumberNM_015032
Gene Symbol PDS5B
Gene ID (NCBI) 23047
RRIDAB_2881111
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9NTI5
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

PDS5B (PDS5 Cohesin Scc1-like Protein B) is a protein associated with sister chromatid cohesion and maintenance of chromosome structure. It plays a significant role in cell cycle regulation, DNA repair, and gene expression. PDS5B interacts with the cohesin complex to ensure the proper separation of sister chromatids during cell division. Additionally, PDS5B is crucial in DNA damage repair, particularly during homologous recombination, helping to maintain genomic stability. It also indirectly affects gene expression and chromatin structure by modulating the function of the cohesin complex. PDS5B is widely expressed during embryonic development and is highly expressed in the brain and testes in adulthood. Its dysfunction is associated with multiple diseases, including Cohesinopathies and Cornelia de Lange syndrome.

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