PMP2 Polyclonal antibody
PMP2 Polyclonal Antibody for IHC, WB, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse, rat, pig and More (1)
Applications
WB, IHC, IF, ELISA
Conjugate
Unconjugated
Cat no : 12717-1-AP
Synonyms
Validation Data Gallery
Tested Applications
Positive WB detected in | pig spinal cord tissue, human brain tissue, mouse testis tissue |
Positive IHC detected in | human gliomas tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
Recommended dilution
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:2000 |
Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
Sample-dependent, check data in validation data gallery |
Published Applications
WB | See 3 publications below |
IHC | See 2 publications below |
IF | See 2 publications below |
Product Information
12717-1-AP targets PMP2 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat, pig samples.
Tested Reactivity | human, mouse, rat, pig |
Cited Reactivity | human, mouse, swine |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | PMP2 fusion protein Ag3411 |
Full Name | peripheral myelin protein 2 |
Calculated molecular weight | 132 aa, 15 kDa |
Observed molecular weight | 15-20 kDa |
GenBank accession number | BC034997 |
Gene symbol | PMP2 |
Gene ID (NCBI) | 5375 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
Background Information
PMP2 (peripheral myelin protein-2, also known as P2) is one of the major proteins of peripheral myelin and appears to be related to the transport of fatty acids or the metabolism of myelin lipids.P2 constitutes up to 15% of total protein of peripheral nervous system (PNS) myelin. It is also present in small amounts in central nervous system (CNS) myelin, being abundant in spinal cord and brain stem myelin. As a structural protein, P2 is thought to stabilize the myelin membranes.
Protocols
Product Specific Protocols | |
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WB protocol for PMP2 antibody 12717-1-AP | Download protocol |
IHC protocol for PMP2 antibody 12717-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
Publications
Species | Application | Title |
---|---|---|
BMC Cancer Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells. | ||
Hum Mol Genet Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy. | ||
Glia A role of peripheral myelin protein 2 in lipid homeostasis of myelinating schwann cells. | ||
Neuron Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction. |