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PRDX6 Monoclonal antibody

PRDX6 Monoclonal Antibody for IF, WB,ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, Pig

Applications

WB, IF,ELISA

Conjugate

Unconjugated

CloneNo.

3C12D3

Cat no : 67499-1-Ig

Synonyms

1 Cys, 1 Cys peroxiredoxin, 1 Cys PRX, 24 kDa protein, aiPLA2, Antioxidant protein 2, AOP2, KIAA0106, Liver 2D page spot 40, NSGPx, p29, peroxiredoxin 6, PRDX6, PRX, Red blood cells page spot 12



Tested Applications

Positive WB detected inA549 cells, HeLa cells, HepG2 cells, K-562 cells, pig brain tissue
Positive IF detected inHeLa cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:5000-1:50000
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

67499-1-Ig targets PRDX6 in WB, IF,ELISA applications and shows reactivity with Human, Pig samples.

Tested Reactivity Human, Pig
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Immunogen PRDX6 fusion protein Ag4727
Full Name peroxiredoxin 6
Calculated molecular weight 224 aa, 25 kDa
Observed molecular weight 25-30 kDa
GenBank accession numberBC035857
Gene symbol PRDX6
Gene ID (NCBI) 9588
Conjugate Unconjugated
Form Liquid
Purification Method Protein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

Background Information

PRDX6 (Peroxiredoxin-6), also named as AOP2 or KIAA0106, is a unique member of the peroxiredoxin family of antioxidants. PRDX6 is highly expressed in liver and protects cells from oxidative damage by reducing H2O2 and various lipid Peroxides (PMID: 17382207). It can form a dimer(PMID:20500660).PRDX6 is expressed in all major organs, with a particularly high level in lung (PMID:15890616). Prdx6 is detected at approximately 24 to 28 kDa, and can be monosumoylated with the molecular mass of about 40 kDa (PMID: 24910119).

Protocols

Product Specific Protocols
WB protocol for PRDX6 antibody 67499-1-IgDownload protocol
IF protocol for PRDX6 antibody 67499-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols