Product Information
30657-1-PBS targets PTGIR in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | PTGIR fusion protein Ag30653 Predict reactive species |
Full Name | prostaglandin I2 (prostacyclin) receptor (IP) |
Calculated Molecular Weight | 386 aa, 41 kDa |
Observed Molecular Weight | 41-45kDa |
GenBank Accession Number | BC075814 |
Gene Symbol | PTGIR |
Gene ID (NCBI) | 5739 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P43119 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
Prostaglandin I2 receptor (PTGIR), also known as IP, is a seven-transmembrane receptor that binds G proteins leading to activation of adenylyl cyclase and an increase in cAMP formation. PTGIR is involved in insulin secretion in pancreatic beta-cells and in permselectivity in glomerular podocytes.