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  • Western Blot (WB) analysis of various lysates using PTPN22 Polyclonal antibody (11783-1-AP)

    WB analysis using 11783-1-AP (same clone as 11783-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11783-1-AP (PTPN22 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11783-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Jurkat cells using PTPN22 Polyclonal antibody (11783-1-AP)

    WB analysis of Jurkat using 11783-1-AP (same clone as 11783-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 11783-1-AP (PTPN22 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11783-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using PTPN22 Polyclonal antibody (11783-1-AP)

    WB analysis using 11783-1-AP (same clone as 11783-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11783-1-AP (PTPN22 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11783-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of Jurkat cells using PTPN22 Polyclonal antibody (11783-1-AP)

    IP experiment of Jurkat using 11783-1-AP (same clone as 11783-1-PBS)

    IP result of anti-PTPN22 (IP:11783-1-AP, 4ug; Detection:11783-1-AP 1:300) with Jurkat cells lysate 3080ug. This data was developed using the same antibody clone with 11783-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lymphoma tissue using PTPN22 Polyclonal antibody (11783-1-AP)

    IHC staining of human lymphoma using 11783-1-AP (same clone as 11783-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 11783-1-AP (PTPN22 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11783-1-PBS in a different storage buffer formulation.

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Product Information

11783-1-PBS targets PTPN22 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen PTPN22 fusion protein Ag2397 Predict reactive species
Full Name protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
Calculated Molecular Weight 82 kDa, 92 kDa
Observed Molecular Weight 100-110 kDa
GenBank Accession NumberBC017785
Gene Symbol PTPN22
Gene ID (NCBI) 26191
RRIDAB_2173378
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9Y2R2
Storage Buffer PBS only, pH 7.3.
Storage ConditionsStore at -80°C.

Background Information

PTPN22(Tyrosine-protein phosphatase non-receptor type 22) is also named as LyP,PEP,PTPN8.It belongs to the protein-tyrosine phosphatase family and non-receptor class 4 subfamily.It acts as negative regulator of T-cell receptor (TCR) signaling.Defects in PTPN22 are a cause of susceptibility to systemic lupus erythematosus (SLE). It has some isoforms produced by alternative splicing with calculated molecular mass of 79-92 kDa, and apparent molecular mass of 100-110 kDa.