Mouse PTPRH Polyclonal antibody, PBS Only

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• Mouse PTPRH Polyclonal antibody, PBS Only (33732-1-PBS)

• 

  WB analysis using 33732-1-AP (same clone as 33732-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 33732-1-AP (PTPRH antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33732-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse colon using 33732-1-AP (same clone as 33732-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 33732-1-AP (PTPRH antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 33732-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse colon using 33732-1-AP (same clone as 33732-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 33732-1-AP (PTPRH antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 33732-1-PBS in a different storage buffer formulation.

PTPRH Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 33732-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, IHC, Indirect ELISA

Synonyms

Receptor-type tyrosine-protein phosphatase H , R-PTP-H, SAP 1

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Product Information

33732-1-PBS targets PTPRH in WB, IHC, Indirect ELISA applications and shows reactivity with mouse samples.

• Tested Reactivity: mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Eg7386

  Product name: Recombinant mouse PTPRH protein

  Source: mammalian cells-derived, V37

  Tag: C-rFc

  Domain: 28-604 aa of NM_207270.2

  Sequence: AGTSVTVDRHAPASSYEFSMWVEKDGVSSSPQIPVTTAAPNPVRNLRVEGQNNISISLSWEPPDQSSLQGLTYWTQCSRHGGQTETRNTTDTSVTVDGLDPGSSYECSVWVEKDGLYSKNETLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQTETRNTADTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLNTSTAPNPVRNLRVEGQNNISISLSWEPPDQPSLQGLTYWAQCSRHGGQTETRNTTDTSITVDGLDPGSSYECSVWVEKDGVYSTNETLSNTTAPNPVRNLRVKSQNNFSISLSWEPPDQPSLQGLIYWAQCSRHGGQTETRNTTDTSVTVDGLDPGFLYKCSVWVEKDGVYSTNETLNTSTVPISASNPVRNLRVEGQNNFSISLSWEPPDQSSLQGLTYWAQCSRHGGQTETRNTADTSVTVDGLDPGSSYECSVWVEKDGVYSTNETLNTSTVPAAVNITSCISTSGGYGVLLTWSCPSGGYESFEVKVGRKWRSENGSLCGKGVTVSDLEPAQSYTATVTTVFKDLKAQSLSTTCHTESAA

• Full Name: protein tyrosine phosphatase, receptor type, H
• Calculated Molecular Weight: 107 kDa
• Observed Molecular Weight: 150-250 kDa
• GenBank Accession Number: NM_207270.2
• Gene Symbol: Ptprh
• Gene ID (NCBI): 545902
• RRID: AB_3743062
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: E9Q0N2
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

PTPRH, also known as SAP-1 (Stomach Cancer-Associated Protein-Tyrosine Phosphatase-1), is a member of the protein tyrosine phosphatase (PTP) family. These enzymes regulate cellular signaling by dephosphorylating tyrosine residues on proteins, counterbalancing kinase activity (PMID: 11278335). PTPRH is classified as a receptor-type PTP, characterized by an extracellular domain, a transmembrane region, and intracellular catalytic domains. In colorectal, gastric, and hepatocellular cancers, PTPRH is often upregulated and linked to poor prognosis (PMID: 12101188). Paradoxically, it may suppress tumorigenesis in other contexts by stabilizing cell adhesion. Overexpression in certain cancers suggests utility as a diagnostic or prognostic marker.