PTPRS Polyclonal antibody, PBS Only

• 

  WB analysis using 31720-1-AP (same clone as 31720-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31720-1-AP (PTPRS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31720-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 31720-1-AP (same clone as 31720-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31720-1-AP (PTPRS antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31720-1-PBS in a different storage buffer formulation.

PTPRS Polyclonal Antibody for WB, Indirect ELISA

Cat No. 31720-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

Receptor-type tyrosine-protein phosphatase sigma, Receptor-type tyrosine-protein phosphatase S, R PTP sigma, R PTP S, PTPSIGMA

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Product Information

31720-1-PBS targets PTPRS in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Recombinant protein

• Full Name: protein tyrosine phosphatase, receptor type, S
• Calculated Molecular Weight: 217 kDa
• Observed Molecular Weight: 140 kDa
• GenBank Accession Number: NM_002850
• Gene Symbol: PTPRS
• Gene ID (NCBI): 5802
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q13332
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Protein tyrosine phosphatase receptor type S (PTPRS, also known as R-PTP-S, PTPSIGMA, and R-PTP-sigma) is an integral membrane protein. It can promote oligomerization by binding to large heparan sulfate proteoglycan structures, and interact with NTRK1/3, PPFIA1/2/3 (PMID: 25385546; 8524829; 9624153). The non-glycosylated molecular weight of PTPRS is 214 kDa, and the extracellular domain can be cleaved near the cell membrane by an endoprotease to generate a glycated 140 kDa protein. Variations and mutations of PTPRS are associated with Alzheimer's disease and cholangiocarcinoma (PMID: 38766183; 35991009).