Filter:
Tested Applications
| Positive WB detected in | MCF-7 cells |
Recommended dilution
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
Product Information
84993-5-RR targets Phospho-YBX1 (Ser102) in WB, ELISA applications and shows reactivity with human samples.
| Tested Reactivity | human |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
Peptide Predict reactive species |
| Full Name | Y box binding protein 1 |
| Calculated Molecular Weight | 324 aa, 36 kDa |
| Observed Molecular Weight | 49 kDa |
| GenBank Accession Number | BC010430 |
| Gene Symbol | YBX1 |
| Gene ID (NCBI) | 4904 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P67809 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
Background Information
YBX1, also known as Y-box binding protein 1, is a multifunctional DNA- and RNA-binding protein and transcription factor that plays a crucial role in various cellular processes, including gene expression, RNA metabolism, and cellular stress response. The phosphorylation of YBX1 at serine 102 (Ser102) is a key post-translational modification that significantly impacts its function and localization within the cell. (PMID: 34680946)
