Polycystin 1 Polyclonal antibody, PBS Only

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  IHC staining of human liver using 22263-1-AP (same clone as 22263-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22263-1-AP (Polycystin 1 antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 22263-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 22263-1-AP (same clone as 22263-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22263-1-AP (Polycystin 1 antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 22263-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 22263-1-AP (same clone as 22263-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 22263-1-AP (Polycystin 1 antibody at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieved with Sodium Citrate buffer (pH 6.0). This data was developed using the same antibody clone with 22263-1-PBS in a different storage buffer formulation.

Polycystin 1 Polyclonal Antibody for IHC, Indirect ELISA

Cat No. 22263-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, Indirect ELISA

Synonyms

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Product Information

22263-1-PBS targets Polycystin 1 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: polycystic kidney disease 1 (autosomal dominant)
• Calculated Molecular Weight: 463 kDa
• GenBank Accession Number: NM_000296
• Gene Symbol: Polycystin 1/PKD1
• Gene ID (NCBI): 5310
• RRID: AB_2879053
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P98161
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Polycystin 1 (PC1) is also named as PKD1, and Autosomal dominant polycystic kidney disease 1 protein, and belongs to the polycystin family. PKD1 and PKD2 are formed component of a heteromeric calcium-permeable ion channel. PKD1 is considered an orphan, atypical G protein coupled receptor complexed with TRPP2 (Polycystin 2 or PKD2), a Ca2+-permeable ion channel (PMID:27214281). PKD1 is involved in renal tubulogenesis (PMID:12482949).