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Product Information
Rheumatoid factors are antibodies directed against the Fc region of immunoglobulin G.
| Tested Reactivity | human |
| Host / Isotype | Human / IgM |
| Class | Recombinant |
| Type | Antibody |
| Immunogen |
N/A Predict reactive species |
| Full Name | Rheumatoid Factor IgM |
| Gene Symbol | |
| Gene ID (NCBI) | |
| RRID | AB_3745150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Affinity purification |
| Storage Buffer | 50mM HEPES, 150mM NaCl, 5mM EDTA, 0.1% CHAPS, 10% Sucrose and 0.1% Proclin300, pH 7.3. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. 20ul sizes contain 0.1% BSA. |
Background Information
Rheumatoid arthritis is an autoimmune disease in which the body's immune system attacks the joints. Rheumatoid factors are the autoantibodies identified in rheumatoid arthritis that target the Fc region of IgG. Among the different rheumatoid factor isotypes, rheumatoid factor IgM is the most clinically used to estimate disease prognosis in rheumatoid arthritis (PMID: 36341420).
