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DSS1 Polyclonal antibody

DSS1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 13639-1-AP

Synonyms

DSS1, ECD, SEM1, SHFD1, Shfdg1, SHFM1, SHSF1



Tested Applications

Positive IHC detected inhuman skin cancer tissue, human cervical cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

13639-1-AP targets DSS1 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen DSS1 fusion protein Ag4573
Full Name split hand/foot malformation (ectrodactyly) type 1
Calculated molecular weight 70 aa, 8 kDa
GenBank accession numberBC032782
Gene symbol SHFM1
Gene ID (NCBI) 7979
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
IHC protocol for DSS1 antibody 13639-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB,IHC

Hum Pathol

DSS1 promoter hypomethylation and overexpression predict poor prognosis in melanoma and squamous cell carcinoma patients.

Authors - Mario Venza
humanWB

Protein Cell

DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.

Authors - Yinghao Zhang
humanWB

BMC Cancer

Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival.

Authors - Andri Rezano

J Med Genet

Absent expression of the osteoblast-specific maternally imprinted genes, DLX5 and DLX6, causes split hand/split foot malformation type I.

Authors - Sawitree Rattanasopha
humanWB, IF

EMBO J

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response.

Authors - Laura R Butler
humanWB

Nature

BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.

Authors - Vaibhav Bhatia
  • KD Validated