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  • KD/KO Validated

ZnT6 Polyclonal antibody

ZnT6 Polyclonal Antibody for WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human and More (3)

Applications

WB,ELISA

Conjugate

Unconjugated

Cat no : 13526-1-AP

Synonyms

MST103, MSTP103, SLC30A6, Zinc transporter 6, ZnT 6, ZNT6



Tested Applications

Positive WB detected inA375 cells, K-562 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2400
Sample-dependent, check data in validation data gallery

Product Information

13526-1-AP targets ZnT6 in WB,ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Cited Reactivity chicken, human, mouse, Yellow catfish
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ZnT6 fusion protein Ag4403
Full Name solute carrier family 30 (zinc transporter), member 6
Calculated molecular weight 460 aa, 50 kDa
Observed molecular weight 51 kDa
GenBank accession numberBC032525
Gene symbol SLC30A6
Gene ID (NCBI) 55676
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

ZnT6 (encoded by SLC30A6) is a member of zinc transporters. ZnT6 is localized on the membrane of the Golgi apparatus as well as cytoplasmic vesicles. It may function in transporting the cytoplasmic zinc into the Golgi apparatus as well as the vesicular compartment. Altered expression of ZnT6 may correlate to neural diseases including Alzheimer's disease. Several isoforms of ZnT6 exist due to the alternative splicing, with MW around 48-56 kDa.

Protocols

Product Specific Protocols
WB protocol for ZnT6 antibody 13526-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Acta Neuropathol Commun

Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.

Authors - Alexandra Grubman
mouseWB

Metallomics

Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?

Authors - Alexandra Grubman
mouseWB

Biol Open

Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.

Authors - Kanninen Katja M KM
human, mouseWB, IHC, IF

J Neurosci Res

Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.

Authors - Masayuki Kaneko
Yellow catfishWB

Biochim Biophys Acta Gene Regul Mech

Transcriptional responses of four slc30a/znt family members and their roles in Zn homeostatic modulation in yellow catfish Pelteobagrus fulvidraco.

Authors - Chang-Chun Song
chickenWB

J Biol Chem

Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation.

Authors - Eisuke Suzuki
  • KO Validated