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  • KD/KO Validated

SLCO4C1 Polyclonal antibody

SLCO4C1 Polyclonal Antibody for WB, IHC, ELISA

Cat No. 24584-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse and More (1)

Applications

WB, IHC, ELISA

OATP H, OATP M1, OATP4C1, OATPX, Organic anion transporter M1, PRO2176, SLC21A20, SLCO4C1

Formulation:  PBS and Azide
PBS and Azide
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inhuman plasma, mouse kidney tissue
Positive IHC detected inhuman kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
Immunohistochemistry (IHC)IHC : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

24584-1-AP targets SLCO4C1 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen

CatNo: Ag20177

Product name: Recombinant human SLCO4C1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-105 aa of BC152989

Sequence: MKSAKGIENLAFVPSSPDILRRLSASPSQIEVSALSSDPQRENSQPQELQKPQEPQKSPEPSLPSAPPNVSEEKLRSLSLSEFEEGSYGWRNFHPQCLQRCNTPG

Predict reactive species
Full Name solute carrier organic anion transporter family, member 4C1
Calculated Molecular Weight 724 aa, 79 kDa
Observed Molecular Weight60-85 kDa
GenBank Accession NumberBC152989
Gene Symbol SLCO4C1
Gene ID (NCBI) 353189
RRIDAB_2879622
Conjugate Unconjugated
FormLiquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6ZQN7
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SLCO4C1 is the only OATP ( organic anion transporting polypeptide) expressed at the human kidney's basolateral side of proximal tubular cells and mediates the excretion of uremic toxins (PMID: 21656517).

Protocols

Product Specific Protocols
WB protocol for SLCO4C1 antibody 24584-1-APDownload protocol
IHC protocol for SLCO4C1 antibody 24584-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

J Ethnopharmacol

Banxia Baizhu Tianma decoction attenuates obesity-related hypertension.

Authors - Yue-Hua Jiang
humanWB

Oncol Rep

Knockdown of SLCO4C1 inhibits cell proliferation and metastasis in endometrial cancer through inactivating the PI3K/Akt signaling pathway.

Authors - Xiang Hu
  • KD Validated
mouseWB

Biochem Biophys Res Commun

PMID: 31540689

Authors - Yuki Kanado
ratWB

World J Gastrointest Pathophysiol

Evaluating the regulation of transporter proteins and P-glycoprotein in rats with cholestasis and its implication for digoxin clearance.

Authors - Parker Giroux
humanIHC

Front Cell Dev Biol

Identification and verification of a prognostic signature based on a miRNA-mRNA interaction pattern in colon adenocarcinoma

Authors - Qiwu Zhao
humanWB

Aging (Albany NY)

Identification and validation of SLCO4C1 as a biological marker in hepatocellular carcinoma based on anoikis classification features

Authors - Tianbing Wang
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