SPINK7 Polyclonal antibody

SPINK7 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 21155-1-AP

Synonyms

ECG2, ECRG 2, ECRG2, ECRG-2, SPINK7

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Validation Data Gallery

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  IHC staining of human oesophagus cancer using 21155-1-AP

  Immunohistochemical analysis of paraffin-embedded human oesophagus cancer tissue slide using 21155-1-AP (SPINK7 antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human oesophagus cancer using 21155-1-AP

  Immunohistochemical analysis of paraffin-embedded human oesophagus cancer tissue slide using 21155-1-AP (SPINK7 antibody) at dilution of 1:200 (under 40x lens).

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Tested Applications

• Positive IHC detected in: human oesophagus cancer tissue; Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

• Immunohistochemistry (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

21155-1-AP targets SPINK7 in IHC, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: SPINK7 fusion protein Ag15727
• Full Name: serine peptidase inhibitor, Kazal type 7 (putative)
• Calculated Molecular Weight: 85 aa, 9 kDa
• GenBank Accession Number: BC109385
• Gene Symbol: SPINK7
• Gene ID (NCBI): 84651
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

SPINK7, also named esophageal cancer-related gene 2 (ECRG 2), is a member of the SPINK protease inhibitor family. It is thought to function as a tumor suppressor gene regulating the protease cascades during carcinogenesis and invasion of esophageal cancer by regulation of migration through urokinase-type plasmin activator/plasmin MAP kinase pathway.