- Featured Product
- KD/KO Validated
STAT6 Polyclonal Antibody for IHC, WB, ELISA
Cat no : 51073-1-AP
D12S1644, IL 4 STAT, STAT6, STAT6B, STAT6C
|Positive WB detected in||NIH/3T3 cells, MCF-7 cells|
|Positive IHC detected in||human spleen tissue, mouse lung tissue, human lung tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:500-1:3000|
|Immunohistochemistry (IHC)||IHC : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
51073-1-AP targets STAT6 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse|
|Host / Isotype||Rabbit / IgG|
|Full Name||signal transducer and activator of transcription 6, interleukin-4 induced|
|Calculated molecular weight||94 kDa|
|Observed molecular weight||100-110 kDa|
|GenBank accession number||BC075852|
|Gene ID (NCBI)||6778|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Aliquoting is unnecessary for -20oC storage.|
STAT6, also named as Signal transducer and activator of transcription 6, is a 847 amino acid protein, which belongs to the transcription factor STAT family. STAT6 forms a homodimer or a heterodimer with a related family member. STAT6 translocates into the nucleus in response to phosphorylation. STAT6 is Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. The antibody could identify about 100 kDa band, similar to the reported in the literature(PMID: 10961983).
Evid Based Complement Alternat Med
Study on the Inhibitory Effects of Ephedra Aconite Asarum Decoction on LPS-Induced Dendritic Cells.
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Molecular analysis of curcumin-induced polarization of murine RAW264.7 macrophages.
IRAK-M alters the polarity of macrophages to facilitate the survival of Mycobacterium tuberculosis.
Eur J Pharmacol
Mechanism of Corilagin interference with IL-13/STAT6 signaling pathways in hepatic alternative activation macrophages in schistosomiasis-induced liver fibrosis in mouse model.
IL-4 Switches Microglia/macrophage M1/M2 Polarization and Alleviates Neurological Damage by Modulating the JAK1/STAT6 Pathway Following ICH.
Onco Targets Ther
CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway.