TBC1D17 Monoclonal antibody, PBS Only

• 

  WB analysis using 60975-3-Ig (same clone as 60975-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60975-3-Ig (TBC1D17 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60975-3-PBS in a different storage buffer formulation.

• 

  WB analysis using 60975-3-Ig (same clone as 60975-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60975-3-Ig (TBC1D17 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60975-3-PBS in a different storage buffer formulation.

TBC1D17 Monoclonal Antibody for WB, Indirect ELISA

Cat No. 60975-3-PBS

Clone No.1H3C1

Host / Isotype

Mouse / IgG2a

Reactivity

human, pig, rabbit

Applications

WB, Indirect ELISA

Synonyms

TBC1 domain family member 17, TBC1 domain family, member 17

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Product Information

60975-3-PBS targets TBC1D17 in WB, Indirect ELISA applications and shows reactivity with human, pig, rabbit samples.

• Tested Reactivity: human, pig, rabbit
• Host / Isotype: Mouse / IgG2a
• Class: Monoclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag14358

  Product name: Recombinant human TBC1D17 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 1-350 aa of BC003516

  Sequence: MEGAGYRVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPGYEPDWAVISTVRPQPCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRM

• Full Name: TBC1 domain family, member 17
• Calculated Molecular Weight: 648 aa, 73 kDa
• Observed Molecular Weight: 73 kDa
• GenBank Accession Number: BC003516
• Gene Symbol: TBC1D17
• Gene ID (NCBI): 79735
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q9HA65
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

TBC1 domain family member 17 (TBC1D17), a Rab GTPase-activating protein, through its catalytic activity, regulates Rab8-mediated endocytic trafficking of transferrin receptor (PMID: 22854040). TBC1D17 also inhibits the trafficking of Shiga toxin from plasma membrane to the Golgi complex through its catalytic activity (PMID: 1756278).