TCEB1 Polyclonal antibody

TCEB1 Polyclonal Antibody for WB, IF, IHC, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 12450-1-AP


EloC, Elongin 15 kDa subunit, Elongin C, SIII, SIII p15, TCEB1

Tested Applications

Positive WB detected inHeLa cells, MCF-7 cells, mouse testis tissue, rat testis tissue
Positive IHC detected inhuman breast cancer tissue, human ovary tumor tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHeLa cells

Recommended dilution

Western Blot (WB)WB : 1:2000-1:12000
Immunohistochemistry (IHC)IHC : 1:50-1:500
Immunofluorescence (IF)IF : 1:200-1:800
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

12450-1-AP targets TCEB1 in WB, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen TCEB1 fusion protein Ag3087
Full Name transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
Calculated Molecular Weight 112 aa, 12 kDa
Observed Molecular Weight 12 kDa
GenBank Accession NumberBC013809
Gene Symbol TCEB1
Gene ID (NCBI) 6921
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TCEB1, also named as RNA polymerase II transcription factor SIII subunit C, belongs to the SKP1 family. It mediates the ubiquitination of ECS-E3 ubiquitin-protein ligase complexes. TCEB1 is overexpressed in prostate cancer cell line PC-3 and breast cancer cell line SK-BR-3. TCEB1 also promotes invasion of prostate cancer cells (PMID:18844214).


Product Specific Protocols
WB protocol for TCEB1 antibody 12450-1-APDownload protocol
IHC protocol for TCEB1 antibody 12450-1-APDownload protocol
IF protocol for TCEB1 antibody 12450-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



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A 12-gene expression signature is associated with aggressive histological in prostate cancer: SEC14L1 and TCEB1 genes are potential markers of progression.

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