Anti-Mouse TCR beta (H57-597)
TCR beta Monoclonal Antibody for FC
Host / Isotype
Armenian Hamster / IgG
Reactivity
Mouse
Applications
FC
Conjugate
Unconjugated
CloneNo.
H57-597
Cat no : 65106-1-Ig
Synonyms
Validation Data Gallery
Tested Applications
Positive FC detected in | mouse splenocytes |
Recommended dilution
Application | Dilution |
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This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
Product Information
65106-1-Ig targets TCR beta in FC applications and shows reactivity with Mouse samples.
Tested Reactivity | Mouse |
Host / Isotype | Armenian Hamster / IgG |
Class | Monoclonal |
Type | Antibody |
Immunogen | Affinity purified TCR from mouse DO-11.10 cells |
Full Name | T-cell receptor beta chain |
Gene Symbol | TCR beta |
Gene ID (NCBI) | 21577 |
RRID | AB_2918405 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Affinity purification |
Storage Buffer | Phosphate based buffer with 0.09% sodium azide, pH 7.2. |
Storage Conditions | Store at 2-8°C. |
Background Information
T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
Protocols
Product Specific Protocols | |
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FC protocol for TCR beta antibody 65106-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |