THSD7A Polyclonal antibody, PBS Only

• 

  WB analysis using 28524-1-AP (same clone as 28524-1-PBS)

  mouse kidney tissue was subjected to SDS PAGE followed by western blot with 28524-1-AP (THSD7A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28524-1-PBS in a different storage buffer formulation.

THSD7A Polyclonal Antibody for WB, Indirect ELISA

Cat No. 28524-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, Indirect ELISA

Synonyms

---

Product Information

28524-1-PBS targets THSD7A in WB, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: THSD7A fusion protein Ag29107
• Full Name: thrombospondin, type I, domain containing 7A
• Calculated Molecular Weight: 185 kDa
• Observed Molecular Weight: 240-250 kDa
• GenBank Accession Number: NM_015204
• Gene Symbol: THSD7A
• Gene ID (NCBI): 221981
• RRID: AB_2918172
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9UPZ6
• Storage Buffer: PBS only , pH 7.3
• Storage Conditions: Store at -80°C.

Background Information

Thrombospondin type-1 domain-containing protein 7A (THSD7A) is a membrane-associated N-glycoprotein with a molecular weight of 250 kDa, which can be cleaved to release a 210-kDa soluble form (PMID: 22194972; 27214550). THSD7A has a role in angiogenesis. It mediates endothelial cell migration and tube formation (PMID: 2002048). THSD7A has been identified as a second autoantigen involved in adult idiopathic membranous nephropathy in addition to PLA2R1 (PMID: 25394321).