TKTL1 Polyclonal antibody

TKTL1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 13819-1-AP

Synonyms

TK 2, TKR, TKT2, TKTL1, Transketolase 2, transketolase like 1, Transketolase like protein 1, Transketolase related protein

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Validation Data Gallery

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  WB analysis using 13819-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 13819-1-AP (TKTL1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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Tested Applications

• Positive WB detected in: HeLa cells, HepG2 cells, MCF-7 cells, U-251 cells

Recommended dilution

• Western Blot (WB): WB : 1:500-1:2000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

13819-1-AP targets TKTL1 in WB, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: TKTL1 fusion protein Ag4913
• Full Name: transketolase-like 1
• Calculated Molecular Weight: 65 kDa
• Observed Molecular Weight: 65 kDa
• GenBank Accession Number: BC025382
• Gene Symbol: TKTL1
• Gene ID (NCBI): 8277
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Transketolase (TKT) is an enzyme that is ubiquitously expressed in all living organisms and has been identified as an important regulator of cancer. The TKT family includes the TKT gene and two TKT-like (TKTL) genes; TKTL1 and TKTL2.The basic components ribose-5-phosphate and acetyl-CoA, which are formed by TKTL1, provide essential building blocks for the formation of new cells. TKTL1 also allows survival in the absence of oxygen (hypoxia).TKTL1 also has been shown to be involved in regulating neuronal development in the cerebral cortex.