MKS3 Polyclonal antibody

MKS3 Polyclonal Antibody for IF, IHC,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IF,ELISA

Conjugate

Unconjugated

Cat no : 13975-1-AP

Synonyms

JBTS6, Meckel syndrome type 3 protein, MECKELIN, MKS3, TMEM67, TNEM67, transmembrane protein 67



Tested Applications

Positive IHC detected inhuman kidney tissue, human hepatocirrhosis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inhTERT-RPE1 cells

Recommended dilution

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

13975-1-AP targets MKS3 in WB, IHC, IF,ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivity human, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen MKS3 fusion protein Ag5009
Full Name transmembrane protein 67
Calculated molecular weight 112 kDa
GenBank accession numberBC032835
Gene symbol TMEM67
Gene ID (NCBI) 91147
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Protocols

Product Specific Protocols
IHC protocol for MKS3 antibody 13975-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanIF

Nat Commun

Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport.

Authors - Christine Insinna
humanWB

Sci Rep

Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly.

Authors - Jie Ran
humanIF

Biophys J

Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening.

Authors - Rueyhung Roc Weng
humanIF

Sci Rep

Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts.

Authors - Elisa Molinari
humanIF

Sci Rep

Superresolution Pattern Recognition Reveals the Architectural Map of the Ciliary Transition Zone.

Authors - T Tony Yang
humanIF

Elife

Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.

Authors - Laura Vuolo