TNFSF11 Recombinant antibody

TNFSF11 {ptg:Brand} Recombinant Antibody for WB, ELISA
Cat No. 84431-5-RR
Clone No.241791B7

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, ELISA

Osteoprotegerin ligand, Osteoclast differentiation factor, OPGL, ODF, CD254

Formulation:  PBS and Azide
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Unconjugated
Size/Concentration: 

-/ -

Freight/Packing: -

Quantity

Please visit your regions distributor:


Tested Applications

Positive WB detected inmouse spleen tissue, mouse liver tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:4000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

84431-5-RR targets TNFSF11 in WB, ELISA applications and shows reactivity with mouse samples.

Tested Reactivity mouse
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Immunogen FusionProtein Predict reactive species
Full Name tumor necrosis factor (ligand) superfamily, member 11
Calculated Molecular Weight35KD
Observed Molecular Weight22 kDa
GenBank Accession NumberNM_011613.3
Gene Symbol Tnfsf11
Gene ID (NCBI) 21943
RRIDAB_3671958
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO35235
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

TNFSF11, known as Tumor Necrosis Factor Superfamily Member 11, also known as RANKL (Receptor Activator of Nuclear Factor-κB Ligand), TRANCE, etc., is a member of the Tumor Necrosis Factor (TNF) superfamily.RANKL is a type II homotrimeric transmembrane protein located primarily at the plasma membrane. RANKL is a type II homotrimeric transmembrane protein located mainly at the plasma membrane, and in addition to the membrane-bound form (mRNAKL), it can also be cleaved by proteolytic cleavage of the cell membrane to produce the soluble form (sRANKL). The membrane-bound form of RANKL is the main form involved in triggering the RANKL/RANK signaling pathway and mediating osteoclastogenesis. Current studies have shown that TNFSF11 acts primarily in the immune and skeletal systems and has been implicated in the pathogenesis of degenerative bone diseases, carcinogenesis, and asthma.

Protocols

Product Specific Protocols
WB protocol for TNFSF11 antibody 84431-5-RRDownload protocol
Standard Protocols
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