TUBB3-specific Antibody 1 Publications

Mouse Monoclonal| Catalog number: 66375-1-Ig |CloneNo.: 1F8G10

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Con: 150 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
fetal human brain tissue, SH-SY5Y cells

Positive IHC detected in:
human cerebellum tissue, human cerebellum tissue, mouse cerebellum tissue

Positive IF detected in:
mouse brain tissue

Recommended dilution:
WB : 1:5000-1:50000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
tubulin, beta 3

Calculated molecular weight:
55

Observed molecular weight:
50-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
TUBB3

Synonyms
beta 4, beta tubulin, MC1R, TUBB, TUBB3, TUBB3-specific, Tubj1, Tubulin beta 3 chain, Tubulin beta III, tubulin, beta 3
Background

TUBB3, the class III β tubulin or Tuj1, is selectively expressed in testis and neurons of the central and peripheral nervous system. It has been widely used as a marker for neurons. Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy. This antibody is specific to TUBB3 but not cross-react with other tubulin isoforms.


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