UGT1A9 Polyclonal antibody, PBS Only

• 

  WB analysis using 16663-1-AP (same clone as 16663-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16663-1-AP (UGT1A9 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16663-1-PBS in a different storage buffer formulation.

UGT1A9 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 16663-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

UGT1*9, EC:2.4.1.17, GNT1, HLUGP4, lugP4

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Product Information

16663-1-PBS targets UGT1A9 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  CatNo: Ag10139

  Product name: Recombinant human UGT1A9 protein

  Source: e coli.-derived, PGEX-4T

  Tag: GST

  Domain: 33-377 aa of BC058844

  Sequence: MDGSHWFTMRSVVEKLILRGHEVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQVRSIYSLLMGSYNDIFDLFFSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGILCHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKNALEIASEILQTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYE

• Full Name: UDP glucuronosyltransferase 1 family, polypeptide A9
• Calculated Molecular Weight: 530 aa, 60 kDa
• Observed Molecular Weight: 60-70 kDa
• GenBank Accession Number: BC058844
• Gene Symbol: UGT1A9
• Gene ID (NCBI): 54600
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: O60656
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

UDP-glucuronosyltransferase 1A9 (UGT1A9) is an enzyme that plays a crucial role in the glucuronidation pathway. It transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. UGT1A9 is part of a complex locus that encodes several UDP-glucuronosyltransferases. The enzyme is active on phenols and is involved in the metabolism of various drugs and endogenous compounds (PMID: 15284532; 12181437; 18004212).