UNC5A-Specific Polyclonal antibody, PBS Only

• 

  WB analysis using 20239-1-AP (same clone as 20239-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20239-1-AP (UNC5A-Specific antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20239-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse brain using 20239-1-AP (same clone as 20239-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 20239-1-AP (UNC5A-Specific antibody) at dilution of 1:100 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20239-1-PBS in a different storage buffer formulation.

UNC5A-Specific Polyclonal Antibody for WB, Indirect ELISA

Cat No. 20239-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, Indirect ELISA

Synonyms

KIAA1976, Netrin receptor UNC5A, Protein unc-5 homolog 1, Protein unc-5 homolog A, UNC5A

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Product Information

20239-1-PBS targets UNC5A-Specific in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

• Tested Reactivity: human, mouse, rat
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen:

  Peptide

• Full Name: unc-5 homolog A (C. elegans)
• Calculated Molecular Weight: 93 kDa
• Observed Molecular Weight: 103 kDa
• GenBank Accession Number: NM_133369
• Gene Symbol: UNC5A
• Gene ID (NCBI): 90249
• RRID: AB_10695050
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q6ZN44
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

UNC5A, also named as KIAA1976 and UNC5H1, belongs to the unc-5 family. It is a receptor for netrin required for axon guidance. It mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The antibody is specific to UNC5A. It has no cross reaction to UNC5B, UNC5C and UNC5D.